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Functional analysis identifies damaging CHEK2 missense variants associated with increased cancer risk
A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair
Treatment with HIV-protease inhibitor nelfinavir identifies membrane lipid composition and fluidity as a therapeutic target in advanced multiple myeloma
Treatment with HIV-protease inhibitor nelfinavir identifies membrane lipid composition and fluidity as a therapeutic target in advanced multiple myeloma
Skipping Nonsense to Maintain Function: The Paradigm of BRCA2 Exon 12
Association of genomic domains in BRCA1 and BRCA2 with prostate cancer risk and aggressiveness
Contact-dependent killing by cytotoxic T lymphocytes is insufficient for EL4 tumor regression in vivo
Enhanced Fatty Acid Scavenging and Glycerophospholipid Metabolism Accompany Melanocyte Neoplasia Progression in Zebrafish
Radiosensitivity is an acquired vulnerability of PARPi-resistant BRCA1-deficient tumors
Loss of chromosome 18q11.2-18q12.1 is predictive for progression-free survival in metastatic colorectal cancer patients treated with bevacizumab
An AXL-specific antibody-drug conjugate shows preclinical anti-tumor activity in non-small cell lung cancer, including EGFR-inhibitor resistant NSCLC
Adoptive Immunotherapy Using PRAME-Specific T Cells in Medulloblastoma
FOXO Transcription Factors Both Suppress and Support Breast Cancer Progression
Substantially improving the cure rate of high-risk BRCA1-like breast cancer patients with personalized therapy (SUBITO) - an international randomized phase III trial
Evaluation of treatment compliance during extended endocrine therapy; secondary analysis of the IDEAL trial
BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer
BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer
Prostate Cancer Patients with Late Radiation Toxicity Exhibit Reduced Expression of Genes Involved in DNA Double-Strand Break Repair and Homologous Recombination
Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice
Safety assessment of extended adjuvant endocrine therapy with letrozole; results of the randomized phase III IDEAL trial (BOOG 2006-05)
10-year follow-up and biomarker discovery for adjuvant endocrine therapy; results of the TEAM trial
Optimal duration of extended letrozole treatment after 5 years of adjuvant endocrine therapy; results of the randomized phase III IDEAL trial (BOOG 2006-05)
Breast cancer after Hodgkin lymphoma: Influence of endogenous and exogenous gonadal hormones on the radiation dose-response relationship
Tumor Eradication by Cisplatin Is Sustained by CD80/86-Mediated Costimulation of CD8(+) T Cells
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