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Genome-wide CRISPR screens define determinants of epithelial-mesenchymal transition mediated immune evasion by pancreatic cancer cells
USP8 promotes cancer progression and extracellular vesicle-mediated CD8+T cell exhaustion by deubiquitinating the TGF-beta receptor T beta RII
OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ
FAF1 Regulates Antiviral Immunity by Inhibiting MAVS but Is Antagonized by Phosphorylation upon Viral Infection
Tumor-derived exosomes antagonize innate antiviral immunity
Breast cancer metastasis suppressor OTUD1 deubiquitinates SMAD7
YAP antagonizes innate antiviral immunity and is targeted for lysosomal degradation through IKK epsilon-mediated phosphorylation
USP4 inhibits SMAD4 monoubiquitination and promotes activin and BMP signaling
The regulation of TGF-beta/SMAD signaling by protein deubiquitination