Leiden University Scholarly Publications

Design thinking in medical education to tackle real world healthcare problems: The MasterMinds Challenge

A biomarker of opioid-induced respiratory toxicity in experimental studies

Respiratory effects of biased ligand oliceridine in older volunteers

Oral oxycodone-induced respiratory depression during normocapnia and hypercapnia

Carbon dioxide tolerability and toxicity in rat and man

Respiratory effects of the atypical tricyclic antidepressant tianeptine in human models of opioid-induced respiratory depression

Respiratory effects of the atypical tricyclic antidepressant tianeptine in human models of opioid-induced respiratory depression

Ketamine psychedelic and antinociceptive effects are connected

Advances in Reversal Strategies of Opioid-induced Respiratory Toxicity

Opioid utility function: methods and implications

Postoperatieve overdosering morfine door familielid

Analgesic and Respiratory Depressant Effects of R-dihydroetorphine A Pharmacokinetic-Pharmacodynamic Analysis in Healthy Male Volunteers

Impact of Temporary Portocaval Shunting and Initial Arterial Reperfusion in Orthotopic Liver Transplantation

Benefit versus Severe Side Effects of Opioid Analgesia Novel Utility Functions of Probability of Analgesia and Respiratory Depression

Esketamine counters opioid-induced respiratory depression

Differential role of nitric oxide in the psychedelic symptoms induced by racemic ketamine and esketamine in human volunteers

Respiratory Effects of the Nociceptin/Orphanin FQ Peptide and Opioid Receptor Agonist, Cebranopadol, in Healthy Human Volunteers

ARA 290 Improves Symptoms in Patients with Sarcoidosis-Associated Small Nerve Fiber Loss and Increases Corneal Nerve Fiber Density (vol 19, pg 334, 2013)

ARA 290 Improves Symptoms in Patients with Sarcoidosis-Associated Small Nerve Fiber Loss and Increases Corneal Nerve Fiber Density

Fentanyl Utility Function: A Risk-Benefit Composite of Pain Relief and Breathing Responses

Influence of ketamine and morphine on descending pain modulation in chronic pain patients: a randomized placebo-controlled cross-over proof-of-concept study

Non-Analgesic Effects of Opioids: Opioid-induced Respiratory Depression

The Dose-Dependent Effect of S(+)-Ketamine on Cardiac Output in Healthy Volunteers and Complex Regional Pain Syndrome Type 1 Chronic Pain Patients

Estimation of the Contribution of Norketamine to Ketamine-induced Acute Pain Relief and Neurocognitive Impairment in Healthy Volunteers