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Role of adenylate cyclase 9 in the pharmacogenomic response to dalcetrapib clinical paradigm and molecular mechanisms in precision cardiovascular medicine
Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals
Plasma apolipoprotein-B is an important risk factor for cardiovascular disease, and its assessment should be routine clinical practice
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
Genetic invalidation of Lp-PLA(2) as a therapeutic target: Large-scale study of five functional Lp-PLA(2)-lowering alleles
Rare and low-frequency coding variants alter human adult height
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension
A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease
Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels
Long-Term Effects of Statin Treatment in Elderly People: Extended Follow-Up of the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER)
Blood Pressure Variability and Cardiovascular Risk in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER)
C-Reactive Protein, Fibrinogen, and Cardiovascular Disease Prediction
Genome-Wide Study of Gene Variants Associated with Differential Cardiovascular Event Reduction by Pravastatin Therapy
The inverse relationship between alanine aminotransferase in the normal range and adverse cardiovascular and non-cardiovascular outcomes
Circulating Interleukin-10 and Risk of Cardiovascular Events A Prospective Study in the Elderly at Risk
Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies
Lipoprotein-associated phospholipase A(2), inflammatory biomarkers, and risk of cardiovascular disease in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER)
Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies
Activation of Hemostasis and Decline in Cognitive Function in Older People
Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials
Unraveling the Directional Link between Adiposity and Inflammation: A Bidirectional Mendelian Randomization Approach
Unraveling the Directional Link between Adiposity and Inflammation: A Bidirectional Mendelian Randomization Approach
Pravastatin and cognitive function in the elderly. Results of the PROSPER study
C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis