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Molecular basis for inhibition of heparanases and β-glucuronidases by siastatin B
The development of a broad-spectrum retaining β-exo-galactosidase activity-based probe.
Design, Synthesis and Structural Analysis of Glucocerebrosidase Imaging Agents
Comprehensive structure-activity-relationship of azaindoles as highly potent FLT3 inhibitors
Comprehensive structure-activity-relationship of azaindoles as highly potent FLT3 inhibitors
Direct Stereoselective Aziridination of Cyclohexenols with 3-Amino-2-(trifluoromethyl)quinazolin-4(3H)-one in the Synthesis of Cyclitol Aziridine Glycosidase Inhibitors
Synthesis of glycosylated 1-deoxynojirimycins starting from natural and synthetic disaccharides
Design and Synthesis of Quenched Activity-based Probes for Diacylglycerol Lipase and alpha,beta-Hydrolase Domain Containing Protein 6
Asymmetric synthesis of lysine analogues with reduced basicity, and their incorporation into proteasome inhibitors
A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase
A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase
Chiral disubstituted piperidinyl ureas: a class of dual diacylglycerol lipase-alpha and ABHD6 inhibitors
Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding
Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding
Photo-crosslinking of clinically relevant kinases using H89-derived photo-affinity probes
Enantioselective synthesis of adamantylalanine and carboranylalanine and their incorporation into the proteasome inhibitor bortezomib
Bis-pyridylethenyl benzene as novel backbone for amyloid-beta binding compounds
Bis-pyridylethenyl benzene as novel backbone for amyloid-beta binding compounds
Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition
Synthesis of 6-Hydroxysphingosine and α-Hydroxy Ceramide Using a Cross-Metathesis Strategy.
In vitro and in vivo comparative and competitive activity-based protein profiling of GH29 alpha-L-fucosidases
The DNAJB6 and DNAJB8 Protein Chaperones Prevent Intracellular Aggregation of Polyglutamine Peptides
Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1
A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo