Leiden University Scholarly Publications

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: Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy

: Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

: Genetic insights into biological mechanisms governing human ovarian ageing

: Genome-wide association study of circulating interleukin 6 levels identifies novel loci

: Genetic studies of leptin concentrations implicate leptin in the regulation of early adiposity

: Classical human leukocyte antigen alleles and C4 haplotypes are not significantly associated with depression

: Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank

: Associations of autozygosity with a broad range of human phenotypes

: A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

: Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits

: Exome-Derived Adiponectin-Associated Variants Implicate Obesity and Lipid Biology

: Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

: Assessment of Bidirectional Relationships Between Physical Activity and Depression Among Adults A 2-Sample Mendelian Randomization Study

: Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

: The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects

: Identification of common genetic risk variants for autism spectrum disorder

: Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

: Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland

: Evidence for increased genetic risk load for major depression in patients assigned to electroconvulsive therapy

: Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity

: Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits

: Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries

: Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

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