Leiden University Scholarly Publications

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: Competitive repopulation and allo-immunologic pressure determine chimerism kinetics after T Cell-depleted allogeneic stem cell transplantation and donor lymphocyte infusion

: Tracking the progeny of adoptively transferred virus-specific T cells in patients posttransplant using TCR sequencing

: Tumor-Infiltrating Lymphocyte Therapy or Ipilimumab in Advanced Melanoma

: Amino acids at position 5 in the peptide/MHC binding region of a public virus-specific TCR are completely inter-changeable without loss of function

: Identification of functional HLA-A*01:01-restricted Epstein-Barr latent membrane protein 2-Specific T-Cell receptors

: Public T-Cell Receptors (TCRs) revisited by analysis of the magnitude of identical and highly-similar TCRs in virus-specific T-Cell repertoires of healthy individuals

: Promiscuity of peptides presented in HLA-DP molecules from different immunogenicity groups is associated with T-cell cross-reactivity

: Magnitude of off-target allo-HLA reactivity by third-party donor-derived virus-specific T cells is dictated by HLA-restriction

: Effect of alemtuzumab-based T-cell depletion on graft compositional change in vitro and immune reconstitution early after allogeneic stem cell transplantation

: HA-1H T-cell receptor gene transfer to redirect virus-specific T cells for treatment of hematological malignancies after allogeneic stem cell transplantation

: A minority of T cells recognizing tumor-associated antigens presented in self-HLA can provoke antitumor reactivity

: Long-term in vitro persistence of magnetic properties after magnetic bead-based cell separation of T cells

: Priming of allo-HLA-DP-specific reactivity from the naive T cell compartment is not exclusively mediated by professional antigen-presenting cells

: What does cell therapy manufacturing cost?

: Immunopeptidome analysis of HLA-DPB1 allelic variants reveals new functional hierarchies

: To bridge, blossom, or boost: that is the question

: Comprehensive diagnostics of acute myeloid leukemia by whole transcriptome RNA sequencing

: Generation and infusion of multi-antigen-specific T cells to prevent complications early after T-cell depleted allogeneic stem cell transplantation-a phase I/II study

: Impact of alemtuzumab pharmacokinetics on T-cell dynamics, graft-versus-host disease and viral reactivation in patients receiving allogeneic stem cell transplantation with an alemtuzumab-based T-cell-depleted graft

: Mutated nucleophosmin 1 as immunotherapy target in acute myeloid leukemia

: The allogeneic HLA-DP-restricted T-cell repertoire provoked by allogeneic dendritic cells contains T cells that show restricted recognition of hematopoietic cells including primary malignant cells

: Loss of the GPI-anchor in B-lymphoblastic leukemia by epigenetic downregulation of PIGH expression

: CD4 Donor Lymphocyte Infusion Can Cause Conversion of Chimerism Without GVHD by Inducing Immune Responses Targeting Minor Histocompatibility Antigens in HLA Class II

: Immune surveillance by autoreactive CD4-positive helper T cells is a common phenomenon in patients with acute myeloid leukemia

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