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allogeneic stem cell transplantation
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Minor histocompatibility antigens to predict, monitor or manipulate GvL and GvHD after allogeneic hematopoietic cell transplantation
Hotspot DNA methyltransferase 3A (DNMT3A) and isocitrate dehydrogenase 1 and 2 (IDH1/2) mutations in acute myeloid leukemia and their relevance as targets for immunotherapy
A transcriptomic based deconvolution framework for assessing differentiation stages and drug responses of AML
Expanding the repertoire reveals recurrent, cryptic, and hematopoietic HLA class I minor histocompatibility antigens
Mapping AML heterogeneity
A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo
Human CD34+-derived complete plasmacytoid and conventional dendritic cell vaccine effectively induces antigen-specific CD8+T cell and NK cell responses in vitro and in vivo
Acquisition of a glycosylated B-cell receptor drives follicular lymphoma toward a dark zone phenotype
Broadly applicable TCR-based therapy for multiple myeloma targeting the immunoglobulin J chain
Quantitative multiple fragment monitoring with enhanced in-source fragmentation/annotation mass spectrometry
An unexplored angle
WT1-specific TCRs directed against newly identified peptides install antitumor reactivity against acute myeloid leukemia and ovarian carcinoma
Glycosphingolipid-glycan signatures of acute myeloid leukemia cell lines reflect hematopoietic differentiation
A broad and systematic approach to identify B cell malignancy-targeting TCRs for multi-antigen-based T cell therapy
T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes
An HLA-A*11:01-binding neoantigen from mutated NPM1 as target for TCR gene therapy in AML
Healthy cells functionally present TAP-independent SSR1 peptides
Permissive HLA-DPB1 mismatches in HCT depend on immunopeptidome divergence and editing by HLA-DM
The SPPL3-defined glycosphingolipid repertoire orchestrates HLA class I-mediated immune responses (vol 54, 132.e1, 2021)
The SPPL3-defined glycosphingolipid repertoire orchestrates HLA class I-mediated immune responses
Identification and validation of expressed HLA-binding breast cancer neoepitopes for potential use in individualized cancer therapy
The SPPL3-defined glycosphingolipid repertoire orchestrates HLA class I-mediated immune responses
Fusion of bacterial flagellin to a dendritic cell-targeting alpha CD40 antibody construct coupled with viral or leukemia-specific antigens enhances dendritic cell maturation and activates peptide-responsive T cells
Optimized whole genome association scanning for discovery of HLA class I-restricted minor histocompatibility antigens
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