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A BRCA1 Coiled-Coil Domain Variant Disrupting PALB2 Interaction Promotes the Development of Mammary Tumors and Confers a Targetable Defect in Homologous Recombination Repair
The RECAP test rapidly and reliably identifies homologous recombination-deficient ovarian carcinomas
C-terminal extensions of Ku70 and Ku80 differentially influence DNA end binding properties
Low dose ionizing radiation strongly stimulates insertional mutagenesis in a gamma H2AX dependent manner
Tumor slice culture system to assess drug response of primary breast cancer
An XRCC4 Splice Mutation Associated With Severe Short Stature, Gonadal Failure, and Early-Onset Metabolic Syndrome
Exploiting DNA repair defects in breast cancer
Functional Ex Vivo Assay to Select Homologous Recombination-Deficient Breast Tumors for PARP Inhibitor Treatment
Similar recombination-activating gene (RAG) mutations result in similar immunobiological effects but in different clinical phenotypes
SIMILAR N-TERMINAL TRUNCATING RAG1 MUTATIONS GIVE RISE TO A BROAD SPECTRUM OF CLINICAL PHENOTYPES
Artemis splice defects cause atypical SCID and can be restored in vitro by an antisense oligonucleotide
A novel radiosensitive SCID patient with a pronounced G(2)/M sensitivity