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Discovery of a photoaffinity probe that captures the active conformation of the cannabinoid CB2 receptor
A monoacylglycerol lipase inhibitor showing therapeutic efficacy in mice without central side effects or dependence
Structural basis of selective cannabinoid CB2 receptor activation
Chemical proteomics reveals antibiotic targets of oxadiazolones in MRSA
Chemical proteomics reveals antibiotic targets of oxadiazolones in MRSA
Role of β-glucosidase 2 in aberrant glycosphingolipid metabolism: model of glucocerebrosidase deficiency in zebrafish
Development of a Cannabinoid-Based Photoaffinity Probe to Determine the D8/9- Tetrahydrocannabinol Protein Interaction Landscape in Neuroblastoma Cells
Synthesis of glycosylated 1-deoxynojirimycins starting from natural and synthetic disaccharides
A chemical genetic screen reveals that iminosugar inhibitors of plant glucosylceramide synthase inhibit root growth in Arabidopsis and cereals
Two-step activity-based protein profiling of diacylglycerol lipase
Design and Synthesis of Quenched Activity-based Probes for Diacylglycerol Lipase and alpha,beta-Hydrolase Domain Containing Protein 6
A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase
A Fluorescence Polarization Activity-Based Protein Profiling Assay in the Discovery of Potent, Selective Inhibitors for Human Nonlysosomal Glucosylceramidase
Chiral disubstituted piperidinyl ureas: a class of dual diacylglycerol lipase-alpha and ABHD6 inhibitors
Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding
Ortho-Carborane-modified N-substituted Deoxynojirimycins
Synthesis of 6-Hydroxysphingosine and α-Hydroxy Ceramide Using a Cross-Metathesis Strategy.
Synthesis of a panel of carbon-13-labelled (glyco)sphingolipids
Synthesis of pseudo-disaccharide analogues of lipid A: haptens for the generation of antibodies with glycosidase activity towards lipid A