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CD137
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Immunotherapy
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T cells
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Beck, R.J.
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Beltman, J.B.
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Mathematical modeling identifies LAG3 and HAVCR2 as biomarkers of T cell exhaustion in melanoma
Modelling the role of cytotoxic T lymphocytes in tumour regression
Mathematical modelling based on in vivo imaging suggests CD137-stimulated cytotoxic T lymphocytes exert superior tumour control due to an enhanced antimitotic effect on tumour cells
Mathematical modelling based on in vivo imaging suggests CD137-stimulated cytotoxic T lymphocytes exert superior tumour control due to an enhanced antimitotic effect on tumour cells
Single-cell imaging of CAR T cell activity in vivo reveals extensive functional and anatomical heterogeneity
Contact-dependent killing by cytotoxic T lymphocytes is insufficient for EL4 tumor regression in vivo