Leiden University Scholarly Publications

Mechanistic early phase clinical pharmacology studies with disease-modifying drugs for neurodegenerative disorders

Quantitative pharmacological modelling for optimizing treatment of sepsis

Treatment optimisation and pharmacogenetics of systemic and intraperitoneal chemotherapy in colorectal cancer

Quantitative pharmacology of antimicrobials

Immune checkpoint inhibitors in mesothelioma

Antibody glycomics signatures of SARS-CoV-2 infection and vaccination

Iron-immune interactions in Alzheimer's disease

Improving diagnostic, prognostic and predictive biomarkers in colorectal cancer

Dynamics and regulation of the oxidative stress response upon chemical exposure

Optimizing triage and treatment strategies in urinary tract infection

Clinical glycomics of antibodies by mass spectometry

Chemokines in Ewing sarcoma

Circulating cells as biomarkers in cardiovascular disease : the difference between men and women

Prognostication in young and elderly breast cancer patients

Genetic and biomarker studies of human longevity

Huntington's disease : functional and structural biomarkers

Huntington's disease : quantifying structural brain changes

Applications of alcohol clamping in early drug development

Clinical applications of DNA methylation in gastrointestinal cancer

Cellular senescence in vitro and organismal ageing

Clinical pharmacology of cannabinoids in early phase drug development

Molecular mechanisms in muscular dystrophy : a gene expression profiling study