BackgroundCataract is the major cause of visual impairment in humans. Phacoemulsification with intraocular lens (IOL) implantation is the standard technique for cataract treatment with a high... Show moreBackgroundCataract is the major cause of visual impairment in humans. Phacoemulsification with intraocular lens (IOL) implantation is the standard technique for cataract treatment with a high success rate. In a few cases, the surgical cataract procedure and lens implantation have been applied in non-human primates. Case DescriptionA +/- 40-year-old female chimpanzee (Pan troglodytes) in captivity was diagnosed with mature cataract optical density (OD) and posterior subcapsular cataract combined with cortical opacities OS after ophthalmic examination. To restore vision and facilitate far- and near sight, phacoemulsification OU with +22.5 diopter (D) IOL implantation OD and + 24 D OS were performed. Despite complicated surgery OD due to posterior capsular rupture, the outcome was successful during 1-year follow-up. The chimpanzee regained adequate vision, normal behavior, and was successfully re-introduced to her group of chimpanzees. ConclusionThis is the first case report of a simultaneous bilateral cataract surgery with IOL implantations in both eyes, targeting emmetropia OS and near vision OD resulting in monovision, in a chimpanzee. Vision was restored without postoperative complications. Show less
Due to special properties, nano-TiO2 will interact with heavy metals and other pollutants in water, thus affecting the environmental behavior and ecotoxicity of these pollutants. However, the exact... Show moreDue to special properties, nano-TiO2 will interact with heavy metals and other pollutants in water, thus affecting the environmental behavior and ecotoxicity of these pollutants. However, the exact manner in which nano-TiO2 affects the bioaccumulation mechanisms of heavy metals is still unclear now. In the present study, quantitative structure bioaccumulation relationship (QSBAR) models were established to explore the relationships between physicochemical parameters of heavy metals and their accumulation in Daphnia magna in the absence and presence of nano-TiO2 at low metal exposure concentrations. The results showed that different physicochemical parameters affected the bioaccumulation of metals in Daphnia magna. The metal accumulation could be described by means of a Comprehensive Parameter composed of seven parameters, i.e., atomic number (AN), relative atomic weight (AW), atomic radius (AR), atomic ionization potential (AN/ΔIP), covalent index (X2r), second ionization energy (I2) and electrochemical potential (E0), in the absence of nano-TiO2, whereas the metal accumulation increased with the increase in Van Der Waals radius (rw) of metals in the presence of nano-TiO2. It was demonstrated that the bioaccumulation mechanism of the metals to Daphnia magna changed in the presence of nano-TiO2. Moreover, the bioaccumulation of more than 85% of the metals increased in the presence of nano-TiO2, but it increased differently for different metals. The present study provides an alternative approach to understand the mechanism of heavy metal bioaccumulation at low metal exposure concentrations and the effect of nano-TiO2 on metal bioaccumulation. Show less
= 79). High (vs. low) social threat led to more "malevolent" creativity (e.g., using bricks as weapons; using intimidation as negotiation tactic). Social threat reduced nonthreat-related creative... Show more= 79). High (vs. low) social threat led to more "malevolent" creativity (e.g., using bricks as weapons; using intimidation as negotiation tactic). Social threat reduced nonthreat-related creative ideation only in Study 1. Study 2 showed that the increase of malevolent creativity was due to the motivation to defend and aggress, and emerged especially among individuals with a high need for cognition. Show less
Previous work on the threat-creativity link has mainly used paradigms in which participants had ample time to generate ideas. However, people under imminent threats have limited time to think of,... Show morePrevious work on the threat-creativity link has mainly used paradigms in which participants had ample time to generate ideas. However, people under imminent threats have limited time to think of, and select, the single best response for actual implementation. In three studies, we examined the effect of imminent threats on the generation and selection of threat responses. Participants facing self-directed or other-directed threats were asked to select one out of two alternative responses that differed on either originality or usefulness to deal with the displayed situation (Studies 1 and 2) or think of and decide on, a fitting response themselves (Study 3). They did so under high or low time pressure (Studies 1–3) and reported their perceived effectiveness of each alternative response in managing the threats (Study 2). Participants selected and generated useful rather than original responses. Whereas time pressure did not moderate this effect, threat direction impacted the selection and generation of imminent threat responses: Self-directed rather than other-directed threats increased the selection and generation of original and creative responses because original responses were seen as more effective. Show less
