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“Alleluia alleluia don’t give you money”. Luoghi e dinamiche di lavoro dentro e fuori le imprese di costruzione statali cinesi in Ghana
Franceschini, C. 2024
“Alleluia alleluia don’t give you money”. Luoghi e dinamiche di lavoro dentro e fuori le imprese di costruzione statali cinesi in Ghana
Article / Letter to editor
open access
Review of Johannesson, N.; Cooper, A. (2023) The Ormulum
Baalen, A.M.W. van 2024
Review of Johannesson, N.; Cooper, A. (2023) The Ormulum
Book review
open access
A suction blister model to characterize epidermal wound healing and evaluate the efficacy of the topical wound healing agent INM-755 in healthy volunteers
Voorde, W. ten; Wind, S.; Abdisalaam, I.; Mancini, A.; Linders, F.; Jansen, M.A.A.; ... ; Rissmann, R. 2024
A suction blister model to characterize epidermal wound healing and evaluate the efficacy of the topical wound healing agent INM-755 in healthy volunteers
Article / Letter to editor
open access
Non-healing wounds represent a substantial medical burden with few effective treatments available. To address this challenge, we developed a novel epidermal wound healing model using suction... Show moreNon-healing wounds represent a substantial medical burden with few effective treatments available. To address this challenge, we developed a novel epidermal wound healing model using suction blisters in healthy volunteers. This model allowed for the comprehensive assessment of wound healing dynamics and the evaluation of INM-755, a topical cream containing cannabinol, as a potential therapeutic agent. Two clinical studies were conducted: an observational study and an interventional study. In both studies, healthy volunteers underwent a suction blister procedure on their lower back, creating open epidermal wounds. Wound healing parameters were assessed using advanced imaging systems. Skin barrier function and perfusion were evaluated through trans epidermal water loss (TEWL) and dynamic optical coherence tomography (D-OCT), respectively. The observational study demonstrated the successful and reproducible Induction of blisters and the removal of epidermal sheet, enabling quantifiable measurements of wound healing parameters over time. Re-epithelialization was observed, revealing recovery of skin barrier function and perfusion. In the interventional study, differences of treatments over time were quantified using the above-described techniques. Despite differences from disease-specific blistering, our developed model provides a valuable platform for studying wound healing mechanisms and assessing novel therapeutic interventions. The sensitivity to treatment effects demonstrated in our study underscores the potential utility of this model in early-phase clinical drug development programs targeting wound healing disorders. Show less
A Petit Bourgeois urban social movement?
Kefford, A. 2024
A Petit Bourgeois urban social movement? The case of Britain’s National Union of small shopkeepers
Part of book or chapter of book
metadata only
Online digital health and informatics education for undergraduate nursing students in China
Shen, H.X.; Chen, C.; Yan, S.J.; Hallensleben, C.; Kleij, R. van der; Li, M.Y.; ... ; Zhou, Y. 2024
Online digital health and informatics education for undergraduate nursing students in China: impacts and recommendations
Article / Letter to editor
open access
Background Digital health plays a vital role in healthcare services. Governments in many countries, including China, are increasingly advocating for the appropriate use of digital technologies to... Show moreBackground Digital health plays a vital role in healthcare services. Governments in many countries, including China, are increasingly advocating for the appropriate use of digital technologies to address significant health system challenges. It is crucial to incorporate digital health education into the curriculum for future nurses to adapt to the changes in the digital medical system. This study aimed to evaluate the impact of an online Digital Health and Informatics Course in China on the knowledge and comprehension of key digital health and informatics topics, self-assessment of nursing informatics competencies, and satisfaction among undergraduate nursing students. The findings of this study provide recommendations for the design and implementation of future digital health education. Methods This study employed a one-group, quasi-experimental mixed-methods design with pre- and postassessments. The participants received digital health and informatics education through six three-hour online sessions in six interactive days, with online self-learning materials in between. An online quiz and focus group discussions pre- and post the course were designed to evaluate the knowledge and comprehension of key digital health and informatics topics. Also, a validated Chinese version of the Self-assessment of Nursing Informatics Competencies Scale was conducted pre- and post-course to assess self-assessment of nursing informatics competencies. Additionally, all students were invited to participate in an online survey with a performance-focused course evaluation form as well as focus group discussions to gather their feedback on the learning experience and their evaluations of the course. Results A total of 24 undergraduate nursing students were enrolled in the course. All students completed all sessions of this course, resulting in an attendance rate of 100%. Additionally, all students completed both pre- and postassessments. In terms of the knowledge and comprehension of key digital health and informatics topics, scores of the quiz on knowledge assessment improved from the pre-test [mean pretest score: 78.33 (SD 6.005)] to the posttest [mean post-test score: 83.17 (SD 4.86)] upon completion of the course (P<0.001). Also, students acknowledged that the course enhanced their knowledge and comprehension of informatics and digital health, the benefits of (nursing) informatics in clinical practice, and the role of health care professionals in informatics and digital health. In terms of self-assessment of nursing informatics competencies, scores on nursing informatics attitudes demonstrated significant improvement (P<0.001). Furthermore, students reported high satisfaction with various aspects of this course, including the opportunity to explore broad horizons in informatics for future careers, engaging in group discussions, and analyzing case studies on the use of informatics and digital health in clinical practice. Conclusions This Online Digital Health and Informatics education effectively improved undergraduate nursing students’ knowledge and comprehension of the key digital health and informatics topics, nursing informatics attitudes in the self-assessment of nursing informatics competency with high levels of satisfaction. In order to ensure that future education in digital health and informatics for nursing students is in line with the technological advancements in clinical settings, it is necessary to foster collaboration between medical school training and clinical practice. This collaboration should involve the use of clinical examples to illustrate advanced digital health applications and the inclusion of practical exercises on the use of digital health technology in clinical settings. Show less
Highly reversible ambipolar photocurrents by modulating Ta in Ba2Bi2–xTaxO6 double perovskites
Guo, T.; Fu, W.T.; Groot, H.J.M. de 2024
Highly reversible ambipolar photocurrents by modulating Ta in Ba2Bi2–xTaxO6 double perovskites
Article / Letter to editor
open access
Molecularly engineered supramolecular thermoresponsive hydrogels with tunable mechanical and dynamic properties
Rijns, L.; Duijs, H.; Lafleur, R.P.M.; Cardinaels, R.; Palmans, A.R.A.; Dankers, P.Y.W.; Su, L. 2024
Molecularly engineered supramolecular thermoresponsive hydrogels with tunable mechanical and dynamic properties
Article / Letter to editor
open access
Synthetic supramolecular polymers and hydrogels in water are emerging as promising biomaterials due to their modularity and intrinsic dynamics. Here, we introduce temperature sensitivity into the... Show moreSynthetic supramolecular polymers and hydrogels in water are emerging as promising biomaterials due to their modularity and intrinsic dynamics. Here, we introduce temperature sensitivity into the nonfunctionalized benzene-1,3,5-tricarboxamide (BTA-EG4) supramolecular system by incorporating a poly(N-isopropylacrylamide)-functionalized (BTA-PNIPAM) moiety, enabling 3D cell encapsulation applications. The viscous and structural properties in the solution state as well as the mechanical and dynamic features in the gel state of BTA-PNIPAM/BTA-EG4 mixtures were investigated and modulated. In the dilute state (c ∼μM), BTA-PNIPAM acted as a chain capper below the cloud point temperature (Tcp = 24 °C) but served as a cross-linker above Tcp. At higher concentrations (c ∼mM), weak or stiff hydrogels were obtained, depending on the BTA-PNIPAM/BTA-EG4 ratio. The mixture with the highest BTA-PNIPAM ratio was ∼100 times stiffer and ∼10 times less dynamic than BTA-EG4 hydrogel. Facile cell encapsulation in 3D was realized by leveraging the temperature-sensitive sol-gel transition, opening opportunities for utilizing this hydrogel as an extracellular matrix mimic. Show less
Place-based knowledge transfer in a local-to-global and knowledge-to-action context
Sievers, Eva; Spierenburg, M.J.; Jhagroe, S.S.; Oudenhoven, A.P. E van 2024
Place-based knowledge transfer in a local-to-global and knowledge-to-action context: key steps and facilitative factors
Article / Letter to editor
open access
Rapid global change threatens to outstrip global efforts to establish sustainable stewardship of social-ecological systems (SES). Place-based research can enhance effectiveness of global... Show moreRapid global change threatens to outstrip global efforts to establish sustainable stewardship of social-ecological systems (SES). Place-based research can enhance effectiveness of global sustainability policies and actions by providing contextualized knowledge underpinning bottom-up solutions. However, the use and transfer of place-based knowledge remains a major challenge. In this study, we analyze place-based knowledge transfer in a local-to-global and knowledge-to-action context. We aim to provide insights on when, how, and why place-based research can inform decision-making at the global scale, and lead to action towards more sustainable and just futures. Our iterative and exploratory methodology involved alternating rounds of literature reviews and interviews with interdisciplinary researchers. We identify four key steps (place-based knowledge production, knowledge synthesis, knowledge use at the global scale, and knowledge revision and lessons learned) and five facilitative factors (bridging organizations, knowledge brokers, boundary organizations, institutionalized knowledge governance and polycentric governance systems), which provide a comprehensive understanding of place-based knowledge transfer. Our conceptual framework provides suggestions on how to set up place-based knowledge transfer to be more effective, complete, and inclusive. Furthermore, our study discusses two major structural challenges that currently inhibit place-based knowledge transfer, and shows ways forward for science and policy to overcome these. We argue that place-based knowledge transfer can be an effective means to undo dominant power relations and the epistemic status quo, and enable a shift from short-termism in science and policy towards more long-term SES goals. Therefore, it is seminal to open up the predominant value system to more diverse knowledge systems, signifying a shift away from global decision-making that is guided by neoliberal capitalist principles and over-emphasizes short-term and individual gains. Finally, it is crucial to prioritize learning over knowing to exploit the long-term value of place-based knowledge transfer. Show less
Grave matters
Meyer, V.H. 2024
Grave matters: ambiguity, modernism, and the quest for moderate Islam in Indonesia
Article / Letter to editor
metadata only
Association between bilirubin and biomarkers of metabolic health and oxidative stress in the MARK-AGE cohort
Schoissengeier, V.; Maqboul, L.; Weber, D.; Grune, T.; Bürkle, A.; Moreno-Villaneuva, M.; ... ; Wagner, K.H. 2024
Association between bilirubin and biomarkers of metabolic health and oxidative stress in the MARK-AGE cohort
Article / Letter to editor
open access
T1 colorectal cancer patients' perspective on information provision and therapeutic decision-making after local resection
Dekkers, N.; Dang, H.; Graaf, M. de; Nobbenhuis, K.; Verhoeven, D.A.; Kraan, J. van der; ... ; Boonstra, J.J. 2024
T1 colorectal cancer patients' perspective on information provision and therapeutic decision-making after local resection
Article / Letter to editor
open access
Background: Decision‐making after local resection of T1 colorectal cancer (T1CRC) isoften complex and calls for optimal information provision as well as active patientinvolvement.Objective: The aim... Show moreBackground: Decision‐making after local resection of T1 colorectal cancer (T1CRC) isoften complex and calls for optimal information provision as well as active patientinvolvement.Objective: The aim was to evaluate the perceptions of patients with T1CRC oninformation provision and therapeutic decision‐making.Methods: This multicenter cross‐sectional study included patients who underwentendoscopic or local surgical resection as initial treatment. Information provision wasassessed using the EORTC QLQ‐INFO25 questionnaire. In patients with high‐riskT1CRC, we evaluated decisional involvement and satisfaction regarding thechoice as to whether to undergo additional treatment after local resection, and thelevel of decisional conflict using the Decisional Conflict Scale.Results: Ninety‐eight patients with T1CRC were included (72% response rate; 79/98 endoscopic and 19/98 local surgical resection; 45/98 high‐risk T1CRC). Mediantime since local resection was 28 months (IQR 18); none had developed recurrence.Unmet information needs were reported by 29 patients (30%; 18 low‐risk, 11 high‐risk), mostly on post‐treatment related topics (follow‐up visits, recovery time,recurrence prevention). After local resection, 24 of the 45 high‐risk patients (53%)underwent additional treatment, while others were subjected to surveillance.Higher‐educated patients were more often actively involved in decision‐making(93% vs. 43%, p = 0.002) and more frequently underwent additional treatment(79% vs. 40%, p = 0.02). Decisional conflict (p = 0.19) and satisfaction (p = 0.78)were comparable between higher‐ and lower‐educated high‐risk patients. Show less
The moral characteristics of environmental sustainability in young people's lives
Collado, S.; Staats, H.J.A.M. 2024
The moral characteristics of environmental sustainability in young people's lives
Part of book or chapter of book
under embargo until 2025-01-18
2025-01-18T00:00:00Z
In this chapter, we frame Pro-environmental behaviors (PEB) as a moral issue and describe the need to understand the development of environmental morality in young populations. We then specify... Show moreIn this chapter, we frame Pro-environmental behaviors (PEB) as a moral issue and describe the need to understand the development of environmental morality in young populations. We then specify factors associated with children’s and adolescents’ environmental morality and their relation with PEB, including young populations’ moral judgments of environmentally harmful actions, their sense of personal obligation to protect nature, and the role of moral environmental emotions. Next, we focus on developmental differences found in environmental morality. We end up by providing suggestions of how formative experiences, especially those organized in contact with nature, may instill a moral stance toward nature in youth. Show less
Spycraft
Akkerman, N.N.W.; Langman, P.F.; Lipscomb, S. 2024
Spycraft: from the Elizabethans to the Restoration
Sound
metadata only
The 16th and 17th centuries were a crucial time for spycraft, full of political intrigue and diplomatic subterfuge. Walsingham was known as a 'Spy Master', but there were many, all vying for... Show moreThe 16th and 17th centuries were a crucial time for spycraft, full of political intrigue and diplomatic subterfuge. Walsingham was known as a 'Spy Master', but there were many, all vying for attention from the Crown.But how did they and their spies operate? Professor Suzannah Lipscomb welcomes Pete Langman and Professor Nadine Akkerman to delve into the practices of espionage and reveal how the line between spy and criminal was easily blurred depending on who was in favour, and who was betrayed.Presented by Professor Suzannah Lipscomb. Show less
Chemosensory systems interact to shape relevant traits for bacterial plant pathogenesis
Munar-Palmer M.; Santamaría-Hernando S.; Liedtke J.; Ortega D.R.; López-Torrejón G.; Rodríguez-Herva J.J.; ... ; López-Solanilla E. 2024
Chemosensory systems interact to shape relevant traits for bacterial plant pathogenesis
Article / Letter to editor
open access
Decolonizing Cameroon’s language policies
Kamdem, S.; Ojongnkpot, C.; Pinxteren, L.M.C. van 2024
Decolonizing Cameroon’s language policies: a critical assessment
Article / Letter to editor
open access
Due to its colonial history and prevalent multilingualism, Cameroon is a country where language policies have profoundly impacted socioeconomic and political life. Cameroon has 273 local languages... Show moreDue to its colonial history and prevalent multilingualism, Cameroon is a country where language policies have profoundly impacted socioeconomic and political life. Cameroon has 273 local languages and two official languages, English and French. The two official languages have been a crystallization point for discontent and civil unrest, leading to secessionist sentiments and violence. In this paper, we assess Cameroon’s language policies, firstly by providing a brief historical and legal overview based in the literature. We then present a new decolonial analytical framework, building on but extending existing theoretical frameworks. Our new analysis shows that a transition to using indigenous languages in formal education and other domains is not necessary at present. However, we argue that such a transition will become unavoidable in future. We show that it will be practically possible to use a limited number of indigenous languages as mediums of instruction, building on existing bilingualisms in the country. We believe these languages should be chosen using rational criteria and we introduce an approximate assessment of which languages are easy to learn and teach, and for speakers of which other languages. The transition we foresee requires planning and preparation. A different approach to Cameroon’s languages may help in building national unity and healing national wounds in the areas of sociolinguistic power-sharing and interregional cohabitation. We expect that our approach also holds benefits for other African countries. Show less
The role of sub-national actors in coordinative Europeanisation
Wolff, S.C.A.; Zardo, F. 2024
The role of sub-national actors in coordinative Europeanisation: insights from the digitalisation of asylum services
Article / Letter to editor
open access
Coordinative Europeanisation is a powerful frame to explain the rapid response of EU institutions in times of permanent emergency. So far, though, little is known about sub-national actors’ role in... Show moreCoordinative Europeanisation is a powerful frame to explain the rapid response of EU institutions in times of permanent emergency. So far, though, little is known about sub-national actors’ role in this process. Moving away from a state-centric approach, this article investigates the role of sub-national actors through the case study of the digital provision of services to asylum seekers. Given the field’s high salience and state-centric nature, this article elucidates the critical role of European sub-national actors, particularly at the municipality level, to accelerate the digital provision of services to refugees. Comparing 3 European cities (Paris, Palermo and Malaga), we argue that sub-national actors can play a role in coordinative Europeanisation and that 2 main mechanisms may enable it. In the cases observed, discursive coordination around humanitarian duty facilitated the emergence of similar digital solutions across countries. Subsequently, horizontal and vertical networking was used by sub-national actors to legitimise their actions and enhance their anchoring in processes of coordinative Europeanisation Show less
Red-to-blue triplet
Andreeva, V.D.; Regeni, I.; Yang, T.; Elmanova, A.; Presselt, M.; Dietzek-Ivansic, B.; Bonnet, S.A. 2024
Red-to-blue triplet: triplet annihilation upconversion for calcium sensing
Article / Letter to editor
open access
Triplet-triplet annihilation upconversion is a bimolecular process converting low-energy photons into high-energy photons. Here, we report a calcium-sensing system working via triplet-triplet... Show moreTriplet-triplet annihilation upconversion is a bimolecular process converting low-energy photons into high-energy photons. Here, we report a calcium-sensing system working via triplet-triplet annihilation (TTA) upconverted emission. The probe itself was obtained by covalent conjugation of a blue emitter, perylene, with a calcium-chelating moiety, and it was sensitized by the red-light-absorbing photosensitizer palladium(II) tetraphenyltetrabenzoporphyrin (PdTPTBP). Sensing was selective for Ca2+ and occurred in the micromolar domain. In deoxygenated conditions, the TTA upconverted luminescence gradually appeared upon adding an increasing concentration of calcium ions, to reach a maximum upconversion quantum yield of 0.0020. Show less
Evaluating the economic landscape of hybrid-electric regional aircraft
Marciello, M.; Cusati, V.; Nicolosi, F.; Saavedra-Rubio, K.; Pierrat, E.; Thonemann, N.; Laurent, A. 2024
Evaluating the economic landscape of hybrid-electric regional aircraft: a cost analysis across three time horizons
Article / Letter to editor
under embargo until 2025-01-16
2025-01-16T00:00:00Z
This article presents the results of a prospective cost analysis of future regional aviation solutions, specifically focusing on hybrid-electric regional aircraft for 50 passengers. The study spans... Show more

This article presents the results of a prospective cost analysis of future regional aviation solutions, specifically focusing on hybrid-electric regional aircraft for 50 passengers. The study spans three time horizons (short term, medium term, long term) and employs a validated workflow to estimate costs for various solutions, including conventional, hybrid-electric, and hydrogen-based architectures. A specialized cost model is introduced to assess the electric components of the powertrain, emphasizing maintenance expenses and energy costs. Despite the environmental promise of hybrid and electric solutions, the results reveal significantly higher direct operating costs (up to 69.8%) compared to conventional options. The study highlights the importance of targeted policies to incentivize sustainable alternatives, suggesting potential solutions such as discouraging kerosene-based aircraft and promoting sustainable aviation fuel. These insights provide valuable guidance for industry stakeholders navigating the path toward a more sustainable and economically viable aviation future.

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    Coronary artery calcium assessment on non-gated chest CT to optimize pre-operative cardiac screening in liver transplantation
    Groen, R.A.; Barbero, F.L.; Fischer, S.E.; Dijkman, P.R.M. van; Bax, J.J.; Tushuizen, M.E.; ... ; Graaf, M.A. de 2024
    Coronary artery calcium assessment on non-gated chest CT to optimize pre-operative cardiac screening in liver transplantation
    Article / Letter to editor
    open access
    BackgroundGuidelines recommend standard pre-operative cardiac screening in all liver transplantation (LT) recipients, despite the relatively low prevalence of obstructive coronary artery disease.... Show moreBackgroundGuidelines recommend standard pre-operative cardiac screening in all liver transplantation (LT) recipients, despite the relatively low prevalence of obstructive coronary artery disease. Most LT recipients often have non-gated computed tomography (CT) performed of the chest and abdomen. This study evaluated the ability of coronary artery calcification (CAC) assessment on consecutively available scans, to identify a selection of low-risk patients, in whom further cardiac imaging can be safely withheld.MethodsLT recipients with prior non-gated CT chest-abdomen were included. CAC was visually scored on a semi-quantitative ordinal scale. Stress myocardial perfusion, coronary CT angiography (CCTA) and invasive coronary angiography (ICA) were used as golden standard. The sensitivity and specificity of CAC to exclude and predict obstructive CAD were assessed. In addition, peri- and postoperative mortality and cardiac events were analyzed.Results149 LT recipients (ranged 31–71 years) were included. In 75% of patients, no CAC and mild CAC could rule out obstructive CAD on CCTA and ICA with 100% certainty. The threshold of mild CAC had a sensitivity of 100% for both CCTA and ICA and a specificity of 91% and 68%, respectively. None of the patients with no or mild calcifications experienced peri- and post-operative cardiac events or died of cardiac causes.ConclusionVisual evaluation of CAC on prior non-gated CT can accurately and safely exclude obstructive CAD in LT recipients. Incorporation of these already available data can optimize cardiac screening, by safely withholding or correctly allocating dedicated cardiac imaging in LT recipients. Thereby, reducing patients' test burden and save health care expenses. Show less
    EHRM 9 juli 2024, Savinovskikh e.a. t. Rusland, nr. 16206/19, ECLI:CE:ECHR:2024:0709JUD001620619, EHRC 2024/188, m.nt. A.C. Hendriks
    Hendriks, A.C. 2024
    EHRM 9 juli 2024, Savinovskikh e.a. t. Rusland, nr. 16206/19, ECLI:CE:ECHR:2024:0709JUD001620619, EHRC 2024/188, m.nt. A.C. Hendriks: ontzeggen van pleegzorg aan transgender man ongerechtvaardigd en niet in belang kinderen
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