Leiden University Scholarly Publications

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Kassa, D.; Ran, L.; Jager, W. de; Broek, T. van den; Jacobi, R.; Mekonen, M.; ... ; Baarle, D. van (2016)

Discriminative expression of whole blood genes in HIV patients with latent and active TB in Ethiopia

Article / Letter to editor
Conclusions: We showed that five genes (CD8A, TIMP2, CCL22, FCGR1A and TNFRSF1A), specifically FCGR1A and CCL22 have the potential to discriminate active TB from non-active TB in HIV patients in Ethiopia and could be used to improve diagnostic tools for active TB in HIV patients, and to understand the pathogenesis of TB/HIV coinfection. (C) 2016 Published by Elsevier Ltd.
Biomarker
Tuberculosis
Host gene
All authors
Kassa, D.; Ran, L.; Jager, W. de; Broek, T. van den; Jacobi, R.; Mekonen, M.; Messele, T.; Haks, M.C.; Ottenhoff, T.H.M.; Baarle, D. van
Date
2016-09-01
Journal
Tuberculosis
Volume
100
Pages
25 - 31
DOI
doi:10.1016/j.tube.2016.06.003