Substantial evidence for the clinical significance of missense variant BRCA1 c.5309G > T p.(Gly1770Val)

Tudini, E.; Moghadasi, S.; Parsons, M.T.; Kolk, L. van der; Ouweland, A.M.W. van den; Niederacher, D.; ... ; Lazaro, C. (2018)

Article / Letter to editor

• BRCA1
• Variant classification
• Multifactorial likelihood analysis
• Breast and ovarian cancer
• Evolutionary conservation

• All authors: Tudini, E.; Moghadasi, S.; Parsons, M.T.; Kolk, L. van der; Ouweland, A.M.W. van den; Niederacher, D.; Feliubadalo, L.; Wappenschmidt, B.; Spurdle, A.B.; Lazaro, C.
• Date: 2018-11-30
• Journal: Breast Cancer Research and Treatment
• Volume: 172
• Issue: 2
• Pages: 497 - 503
• DOI: doi:10.1007/s10549-018-4903-y