Integrated semi-physiological pharmacokinetic model for both sunitinib and its active metabolite SU12662

Yu, H.X.; Steeghs, N.; Kloth, J.S.L.; Wit, D. de; Hasselt, J.G.C. van; Erp, N.P. van; ... ; Huitema, A.D.R. (2015)

Article / Letter to editor

• modelling
• pharmacokinetics
• semi-physiological model
• SU12662
• sunitinib
• therapeutic drug monitoring

• All authors: Yu, H.X.; Steeghs, N.; Kloth, J.S.L.; Wit, D. de; Hasselt, J.G.C. van; Erp, N.P. van; Beijnen, J.H.; Schellens, J.H.M.; Mathijssen, R.H.J.; Huitema, A.D.R.
• Date: 2015-05-31
• Journal: British Journal of Clinical Pharmacology
• Volume: 79
• Issue: 5
• Pages: 809 - 819
• DOI: doi:10.1111/bcp.12550