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Diagnosis and classification of axial spondyloarthritis : imaging and non-imaging features
modalities. We have studied multiple elements diagnosing axSpA among patients presenting
with chronic back pain. We have emphasized two main themes: (1) the importance of clinical
SpA features; and (2) the contribution of imaging to an axSpA diagnosis and classification.
We have learned how rheumatologists use imaging results in their diagnostic considerations
and thereby have helped reduce certain fears regarding the way diagnosis is made in clinical
practice. We have shown that the use of MRI-spine in classification is not efficient. The
common thread in all of the studies in this thesis is that axSpA diagnosis is the interaction
between the clinical aspects of chronic back pain and imaging findings highly suggestive of
axSpA. Clinicians should be aware of mindlessly ‘stacking up’ SpA features in chronic back
pain patients...Show moreIn this thesis the focus was on diagnosing axSpA early using clinical features as well as imaging
modalities. We have studied multiple elements diagnosing axSpA among patients presenting
with chronic back pain. We have emphasized two main themes: (1) the importance of clinical
SpA features; and (2) the contribution of imaging to an axSpA diagnosis and classification.
We have learned how rheumatologists use imaging results in their diagnostic considerations
and thereby have helped reduce certain fears regarding the way diagnosis is made in clinical
practice. We have shown that the use of MRI-spine in classification is not efficient. The
common thread in all of the studies in this thesis is that axSpA diagnosis is the interaction
between the clinical aspects of chronic back pain and imaging findings highly suggestive of
axSpA. Clinicians should be aware of mindlessly ‘stacking up’ SpA features in chronic back
pain patients in order to avoid unnecessary (biologic) treatment. Additional studies are needed
to investigate the numerous phenotypes of axSpA and to predict in which chronic back pain
patient axSpA diagnosis is likely.Show less
- All authors
- Ez-Zaitouni, Z.
- Supervisor
- Heijde, D.M.F.M.; Landewé, R.B.M.
- Co-supervisor
- Gaalen, F.A. van
- Committee
- Allaart, C.F.; Huizinga, T.W.J.; Sande, M.G. van de; Boers, M.
- Qualification
- Doctor (dr.)
- Awarding Institution
- Faculty of Medicine, Leiden University Medical Center (LUMC) , Leiden University
- Date
- 2019-09-17
- ISBN
- 9789463237390