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Molendijk, M.L.; Fried, E.I.; Van der Does, W. (2018)

The SMILES trial: Do recruitment practices explain the remarkably large effect?

Article / Letter to editor
The SMILES trial showed substantial improvement of depressive symptoms following seven consultations on healthy dieting. The very large effect size on depression reduction seems remarkable and we suggest that selectively induced expectancy and a loss of blinding have contributed to the observed effect.
All authors
Molendijk, M.L.; Fried, E.I.; Van der Does, W.
Date
2018-12-28
Journal
BMC Medicine
Volume
16
Pages
e243
DOI
doi:10.1186/s12916-018-1221-5
Link
https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-018-1221-5