Reversible noncovalent assemblies for imaging applications

Rood, M.T.M. (2018)

Doctoral Thesis

Molecular imaging plays a vital role in current medical diagnostics. There is a constant need for new and improved molecular imaging agents in terms of resolution, specificity, stability, safety and cost. The research described in this thesis deals with the development of activatable luminescence lifetime imaging agents as well as with the use of supramolecular chemistry to introduce cell surface modifications to living cells. 

• Molecular imaging
• Lifetime imaging
• Activatable imaging
• Phosphorescence
• Iridium
• Cell surface engineering

• All authors: Rood, M.T.M.
• Supervisor: Bloem, J.L.; Huskens, J.
• Co-supervisor: Leeuwen, F.W.B.
• Committee: Bouwman, E.; Velders, A.H.; Tanke, H.J.; Koning, F.
• Qualification: Doctor (dr.)
• Awarding Institution: Faculty of Medicine, Leiden Uiversity Medical Center (LUMC), Leiden University
• Date: 2018-12-20
• Sponsorship: NWOnano STW 11435