Nicotiana benthamiana α-galactosidase A1.1 can functionally complement human α-galactosidase A deficiency associated with Fabry disease

Kytidou, K.; Beekwilder, J.; Artola, M.; Meel, E. van; Wilbers, R.H.P.; Moolenaar, G.F.; ... ; Aerts, J.M.F.G. (2018)

Article / Letter to editor

• glycoside hydrolase
• plant
• human
• enzyme inhibitor
• glycolipid
• fluorescence
• protein expression
• enzyme purification
• enzyme structure
• -galactosidase
• enzyme-replacement therapy
• Fabry disease
• glycosphingolipids
• Nicotiana benthamiana
• homologue
• lysosomal storage disorder
• recombinant enzyme
• glycosphingolipid

• All authors: Kytidou, K.; Beekwilder, J.; Artola, M.; Meel, E. van; Wilbers, R.H.P.; Moolenaar, G.F.; Goosen, N.; Ferraz, M.J.; Katzy, R.; Voskamp, P.; Florea, B.I.; Hokke, C.H.; Overkleeft, H.S.; Schots, A.; Bosch, D.; Pannu, N.; Aerts, J.M.F.G.
• Date: 2018-06-29
• Journal: Journal of Biological Chemistry
• Volume: 293
• Issue: 26
• Pages: 10042 - 10058
• DOI: doi:10.1074/jbc.RA118.001774
• Link: http://www.jbc.org/content/293/26/10042