Novel treatments for advanced thyroid cancer and elucidation of biomarkers

Schneider, T.C. (2018)

Doctoral Thesis

In this thesis we describe the latest developments in the field of advanced thyroid cancer. Several clinical trials with sorafenib and everolimus were performed. The relation between clinical outcome and mutational status was analyzed. Furthermore, the pharmacokinetics of everolimus in patients with advanced thyroid cancer was described.

• Thyroid cancer
• Sorafenib
• Everolimus
• Clinical trial
• Targeted therapy
• Pharmacokinetics

• All authors: Schneider, T.C.
• Supervisor: Morreau, J.; Hoeven, J.J.M. van der
• Co-supervisor: Kapiteijn, E.
• Committee: Links, T.P.; Ottevanger, P.B.; Gelderblom, A.J.
• Qualification: Doctor (dr.)
• Awarding Institution: Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University
• Date: 2018-10-31
• ISBN (print): 9789402812350