Risk factors of venous thrombosis in the elderly

Karasu, A. (2018)

Doctoral Thesis

In this thesis the risk factors of venous thrombosis will be discussed in the general and particularly the elderly population. The goal of this thesis is to provide insights on risk factors of thrombosis in the elderly population, in order to advance our basic understanding of physiological age-related changes that increase the risk of venous thrombosis and which may ultimately lead to improved personalized interventions. In this chapter firstly background information will be provided on risk factors for venous thrombosis, focussing specifically on age as a risk factor. Secondly, the role of veins and venous valves in the development of venous thrombosis will be discussed and thirdly, global assays as a potential tool to identify patients at high risk for venous thrombosis will be considered. The study populations used in this thesis will discussed, and an outline of this thesis will be provided.

• Venous thrombosis
• Elderly
• Risk factors
• Pulmonary embolism
• Clot lysis time
• Epidemiology
• Aging

• All authors: Karasu, A.
• Supervisor: Rosendaal, F.R.
• Co-supervisor: Hylckama Vlieg, A. van
• Committee: Srámek, A.; Cannegieter, S.C.; Meijer, K.; Bossuyt, P.M.M.
• Qualification: Doctor (dr.)
• Awarding Institution: Klinische Epidemiologie, Medicine / Leiden University Medical Center (LUMC), Leiden University
• Date: 2018-07-04
• ISBN (print): 9789087597733