Tailoring adjuvant therapy for hormone receptor-positive breast cancer

Blok, E.J. (2018)

Doctoral Thesis

Although the survival of breast cancer has improved the past decades, there is still major over- and undertreatment for the majority of patients. The aim of this research was to identity the most optimal adjuvant endocrine therapy, with regard to the optimal duration of therapy and the selection of subgroups who require selected therapy. 

• Breast cancer
• Adjuvant_endocrine therapy
• Aromatase inhibitors
• Tamoxifen
• Tumour infiltrating lymphocytes
• Estrogen receptor
• Gene expression profiling

• All authors: Blok, E.J.
• Supervisor: Velde, C.J.H. van de
• Co-supervisor: Kroep, J.R.; Kuppen, P.J.K.
• Committee: Smit, V.T.H.B.M.; Linn, S.C.; Hoeven, J.J.M. van der
• Qualification: Doctor (dr.)
• Awarding Institution: Heelkunde en Medische Oncologie, Medicine / Leiden University Medical Center (LUMC), Leiden University
• Date: 2018-05-31
• ISBN (print): 9789463323345
• Sponsorship: Pfizer, Philips, Agendia, Chipsoft