Fetal and neonatal alloimmune thrombocytopenia : towards implementation of screening in pregnancy

Kamphuis, M.M. (2017)

Doctoral Thesis

This thesis describes new knowledge of FNAIT in preparation of a national wide screening program. It illustrates the prevalence of FNAIT among pregnant women and the risk of adverse outcome, outlines current management, evaluates risks of missing a diagnosis of FNAIT, studies the efficacy of a lower dose of immunoglobulins in preventing bleedingcomplications,shows the time of bleeding onset of fetal ICH during pregnancy and illustrates the longterm outcome of children with ICH.

 

• FNAIT
• Intracranial haemorrhage
• Bleeding
• Immunoglobulins
• Management
• Delayed diagnosis
• Burden disease
• Screening

• All authors: Kamphuis, M.M.
• Supervisor: Oepkes, D.
• Co-supervisor: Lopriore, E.
• Committee: Zwaginga, J.J.; Husebekk, A.; Schoot, C.E. van der; Lith, J.M.M. van
• Qualification: Doctor (dr.)
• Awarding Institution: Medicine, Leiden University
• Date: 2017-05-23
• ISBN (print): 9789462336193
• Sponsorship: Dhr. A Bezemer; BMA (Mosos); Bayer; Chipsoft