Multimodal CT imaging for diagnosis, treatment and prognosis in ischemic stroke

Holswilder, G. (2025)

Doctoral Thesis

Stroke is a prevalent neurological disorder of which transient ischemic stroke (TIA) and ischemic stroke constitute the majority. Ischemic stroke requires acute medical treatment to resolve the blood clot and thereby increase the chance of good clinical recovery. Sophisticated techniques have become available over the years and an increasing number of CT imaging characteristics have improved stroke management. The aim of this thesis was to identify novel CT imaging parameters to provide more insight into the diagnosis, prognosis, and treatment selection in patients with TIA or acute ischemic stroke. Advances in CT imaging techniques provide an increasing amount of valuable information that can support the neurologist and interventionalist to optimize patient management.

• Ischemic Stroke
• Transient Ischemic Attack
• Atherosclerosis
• Computed tomography angiography
• Cardioembolism
• Migraine
• Endovascular treatment
• Vascular elongation

• All authors: Holswilder, G.
• Supervisor: Wermer, M.J.H.
• Co-supervisor: Walderveen, M.A.A. van; Kruyt, N.D.
• Committee: Goeman, J.J.; Atsma, D.E.; Hertog, M.H. den; Schaaf, I.C. van der
• Qualification: Doctor (dr.)
• Awarding Institution: Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University
• Date: 2025-10-16
• ISBN (print): 9789465225708