Development and use of biomarkers in clinical development of new therapies for chronic airway disease

Zuiker, Robertus Gerardus Johannes Antonius (2016)

Doctoral Thesis

This thesis describes attempts to identify novel pathophysiology based biomarkers for chronic airway disease by applying newer detection techniques. It appears that such an approach may be worthwhile to pursue. Further, it shows that application of biomarkers allows effective development of new therapies in chronic airway disease.

• Inflammation
• Allergen challenges
• Biomarkers
• COPD
• Asthma

• All authors: Zuiker, Robertus Gerardus Johannes Antonius
• Supervisor: Burggraaf, J.; Cohen, A.F.
• Qualification: Doctor (dr.)
• Awarding Institution: Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University
• Date: 2016-04-06