Improving care for red blood cell alloimmunized pregnant women

Slootweg, Y.M. (2023)

Doctoral Thesis

The aim of this dissertation was to identify gaps in knowledge and room for improvements in certain aspects of the current system of prevention and care regarding RBC alloimmunization in pregnancy. The focus in this thesis was to evaluate the performance of new measures in the prevention program, the follow-up with laboratory monitoring in alloimmunized pregnancies and the counseling of pregnant women and their partners, in cases of RBC alloimmunization.

• Red blood cell alloimmunization
• Hemolytic disease of the fetus and newborn
• Prenatal screening
• Rhesus-D
• Kell immunization
• Pregnancy complications
• Fetomaternal haemorrhage
• Anti-D prophylaxis
• Anti-D donors
• Prevention

• All authors: Slootweg, Y.M.
• Supervisor: Haas, M. de
• Co-supervisor: Kamp, I.L. van; Koelewijn, J.M.
• Committee: Bom, J.G. van der; Lopriore, E.; Verweij, E.J.T.; Verhoeven, C.; Nieuwenhuijze, M.; Wouters, M.G.A.J.
• Qualification: Doctor (dr.)
• Awarding Institution: Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University
• Date: 2023-09-13
• Sponsorship: Sanquin Research; Department of Obstetrics