Buprenorphine: a treatment and cause of opioid-induced respiratory depression

Dahan, A.; Lemmen, M. van; Jansen, S.; Simons, P.; Schrier, R. van der (2022)

Other

Buprenorphine is a partial agonist at the mu opioid receptor. Due to its relatively low maximum effect on respiratory depression it is considered by some to be a safe opioid. But it can produce serious respiratory depression, particularly when combined with sedatives such as benzodiazepines.

• benzodiazepine
• breathing
• buprenorphine
• opioid-induced respiratory depression
• partial agonism

• All authors: Dahan, A.; Lemmen, M. van; Jansen, S.; Simons, P.; Schrier, R. van der
• Date: 2022-03-01
• Title of host publication: British Journal of Anaesthesia
• Volume: 128
• Issue: 3
• Pages: 402 - 404
• DOI: doi:10.1016/j.bja.2021.10.029