Considerations for future studies on the effect of late phase oxygen strategies on retinopathy of prematurity

Nusman, C.M.; Schalij-Delfos, N.E.; Groenwold, R.H.H.; Onland, W. (2022)

Article / Letter to editor

Strategies to ensure high intraocular oxygen delivery to the developing retina after 32 weeks gestational age, such as higher saturation targets and/or higher hemoglobin levels, are hypothesized to prevent ophthalmological treatment for retinopathy of prematurity (ROP). This short report summarizes the current evidence of these strategies, and discusses possibilities of future studies. A large sample size would be required and therefore the feasibility of a future randomized controlled trial is questioned.

• retinopathy
• prematurity
• oxygen
• hemoglobin
• saturation
• study design

• All authors: Nusman, C.M.; Schalij-Delfos, N.E.; Groenwold, R.H.H.; Onland, W.
• Date: 2022-10-24
• Journal: Frontiers in Pediatrics
• Volume: 10
• DOI: doi:10.3389/fped.2022.975613