Optimising preoperative systemic therapy for breast cancer

Charehbili, A. (2015)

Doctoral Thesis

This thesis was divided in two parts. Part I demonstrated benefit of zoledronic acid addition to chemotherapy in terms of pathological response in postmenopausal women. Part II is all about neoadjuvant endocrine therapy, and discusses the optimal duration of this treatment and the information on treatment efficacy that aromatase-inhibitor specific adverse events may provide.

• Zoledronic acid
• Aromatase inhibitors
• Bisphosphonates
• Neoadjuvan
• Chemotherapy
• Breast cancer

• All authors: Charehbili, A.
• Supervisor: Velde, C.J.H. van de; Nortier, J.W.R.
• Co-supervisor: Kroep, J.R.
• Qualification: Doctor (dr.)
• Awarding Institution: Faculty of Medicine (LUMC), Leiden University
• Date: 2015-09-16
• ISBN (print): 9789462330191
• Sponsorship: The printing of this thesis was made possible by the departments of Medical Oncology and Surgery of the Leiden Universtity Medical Center, Boehringer Ingelheim, Chipsoft, Philips, Novartis, Pfizer and Galephar.