The ins and outs of mutlivesicular bodies

Perrin, P.C. (2022)

Doctoral Thesis

In this thesis I explored the ins and outs of the multivesicular body, the pathways that intersect at this central endocytic compartment, the dynamics governing its lumen and how such processes impact various fields of cell biology and disease.

• Endosome
• Lysosome
• Multivesicular body
• Intraluminal vesicle
• Extracellular vesicle
• Exosome
• Endolysosome
• Retrofusion
• Endocytic network
• MHC class II

• All authors: Perrin, P.C.
• Supervisor: Neefjes, J.J.C.
• Co-supervisor: Berlin, I.
• Committee: Dijke, P. ten; Borst, J.G.; Kant, R. van der; Reits, E.A.
• Qualification: Doctor (dr.)
• Awarding Institution: Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University
• Date: 2022-10-27
• ISBN (print): 9789464586497