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Vanneste, B.G.L.; Lopez-Yurda, M.; Tan, I.B.; Balm, A.J.M.; Borst, G.R.; Rasch, C.R. (2016)

Irradiation of localized squamous cell carcinoma of the nasal vestibule

Article / Letter to editor
Background. The purpose of this study was to evaluate the long-term results of primary radiotherapy treatment for squamous cell carcinoma (SCC) of the nasal vestibule.Methods. Eighty-one patients were treated with external beam radiotherapy (EBRT) and/or interstitial radiotherapy (IRT) for a primary, localized, Wang classified SCC of the nasal vestibule.Results. Median follow-up was 38 months. T1 tumors were treated with IRT: we observed 1 local failure (at 13 months) among 48 patients (5-year local control rate of 97%). Most T2 tumors (20 of 26) were treated with EBRT. There were 8 local recurrences among 26 patients (5-year local control rate of 68%). For the T3 tumors (n = 7; all treated with EBRT), we observed local recurrence in 2 patients (5-year local control rate of 53%). The late-term side effects were relatively mild.Conclusion. Local primary radiotherapy (either IRT for T1 or EBRT for T2/3) is an adequate treatment for SCC of the nasal vestibule with little late sequelae....Show moreBackground. The purpose of this study was to evaluate the long-term results of primary radiotherapy treatment for squamous cell carcinoma (SCC) of the nasal vestibule.Methods. Eighty-one patients were treated with external beam radiotherapy (EBRT) and/or interstitial radiotherapy (IRT) for a primary, localized, Wang classified SCC of the nasal vestibule.Results. Median follow-up was 38 months. T1 tumors were treated with IRT: we observed 1 local failure (at 13 months) among 48 patients (5-year local control rate of 97%). Most T2 tumors (20 of 26) were treated with EBRT. There were 8 local recurrences among 26 patients (5-year local control rate of 68%). For the T3 tumors (n = 7; all treated with EBRT), we observed local recurrence in 2 patients (5-year local control rate of 53%). The late-term side effects were relatively mild.Conclusion. Local primary radiotherapy (either IRT for T1 or EBRT for T2/3) is an adequate treatment for SCC of the nasal vestibule with little late sequelae. (C) 2015 Wiley Periodicals, Inc.Show less
nasal vestibule
squamous cell carcinoma
external beam radiotherapy
interstitial radiotherapy
All authors
Vanneste, B.G.L.; Lopez-Yurda, M.; Tan, I.B.; Balm, A.J.M.; Borst, G.R.; Rasch, C.R.
Date
2016-04-01
Journal
Head and Neck
Volume
38
Pages
E1870 - E1875
DOI
doi:10.1002/hed.24337