Reliability and agreement of proton density-weighted vs. gadolinium-enhanced T1-weighted MRI in hand osteoarthritis. An OMERACT MRI special interest group reliability exercise

Maugesten, O.; Pedersen, S.J.; Stoenoiu, M.S.; Kroon, F.; Mathew, A.J.; Genant, H.K.; ... ; Haugen, I.K. (2021)

Article / Letter to editor

Objectives: To compare reliabilities of assessing synovitis in hand osteoarthritis (OA) using Magnetic Resonance Imaging (MRI) with/without gadolinium (Gd). Methods: Three readers scored synovitis on non-enhanced two-dimensional (2D) proton density (PD)weighted MRI and Gd-enhanced (3D) MRI of hand joints in 20 patients. Inter-reader reliabilities were examined. Results: Reliability was good for Gd-enhanced MRI, but poor for non-enhanced PD-weighted MRI (intraclass correlation coefficient 0.83 and 0.21, respectively). Agreement between the two sequences was poor (weighted kappa 0.18). Conclusion: Gd-enhanced MRI was more reliable than PD-weighted MRI for assessing synovitis. Gd-enhancement, but also resolution and tissue contrast, might have contributed to this. (c) 2021 Elsevier Inc. All rights reserved.

• OMERACT
• Osteoarthritis
• MRI
• Hand
• Synovitis

• All authors: Maugesten, O.; Pedersen, S.J.; Stoenoiu, M.S.; Kroon, F.; Mathew, A.J.; Genant, H.K.; Conaghan, P.G.; Gandjbakhch, F.; Kloppenburg, M.; Peterfy, C.; Ostergaard, M.; Haugen, I.K.
• Date: 2021-08-01
• Journal: Seminars in Arthritis and Rheumatism
• Volume: 51
• Issue: 4
• Pages: 929 - 932
• DOI: doi:10.1016/j.semarthrit.2021.05.007