Leiden University Scholarly Publications

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Sijp, M.P.L. van der (2021)

Prognostics of recovery in hip fracture patients

Doctoral Thesis
Proximal femoral fractures (often denoted as hip fractures) are amongst the most prevalent fractures in older patients and associated with significant mortality and morbidity.

Failure to recover to prefracture levels of function has important social and economic implications, as these patient’s risk losing their independence and self-reliance. The primary aim of this thesis is to provide a better understanding of the factors relevant for the functional prognosis of patients with a proximal femoral fracture.
This thesis covers two parts, focusing on the effects of surgical aspects and patient demographics.
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Outcomes of previously performed studies on prognostic factors of recovery proved hard to compare. This can be attributed to the high level of heterogeneity and methodology of these studies, for instance in the method to objectify recovery. For the studies in this thesis, we have opted to compare outcomes with the patients’ individual prefracture level of...Show moreProximal femoral fractures (often denoted as hip fractures) are amongst the most prevalent fractures in older patients and associated with significant mortality and morbidity.

Failure to recover to prefracture levels of function has important social and economic implications, as these patient’s risk losing their independence and self-reliance. The primary aim of this thesis is to provide a better understanding of the factors relevant for the functional prognosis of patients with a proximal femoral fracture.
This thesis covers two parts, focusing on the effects of surgical aspects and patient demographics.
​​​​​​​
Outcomes of previously performed studies on prognostic factors of recovery proved hard to compare. This can be attributed to the high level of heterogeneity and methodology of these studies, for instance in the method to objectify recovery. For the studies in this thesis, we have opted to compare outcomes with the patients’ individual prefracture level of function. Surgical aspects, such as different approaches to place a prosthesis, seemed to have a reserved effect on recovery. Factors which seemed of conclusive relevance were health scores based on the comorbidity and prefracture level of function. This emphasizes the importance of a holistic and geriatric approach for patients with proximal hip fractures.
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Proximal femoral fracture
Hip fracture
Functional recovery
Functional outcome
Biomarkers
Prognostics
Hip fracture surgery
Hip prosthesis
Arthroplasty
Prognostic factors
All authors
Sijp, M.P.L. van der
Supervisor
Achterberg, W.P.
Co-supervisor
Eijk, M. van; Niggebrugge, A.H.P.
Committee
Dekkers, O.; Munster, B.C. van; Schols, J.M.G.A.; Hegeman, J.H.
Qualification
Doctor (dr.)
Awarding Institution
Faculty of Medicine, Leiden University Medical Center (LUMC), Leiden University
Date
2021-09-02
ISBN (print)
9789463615532

Funding

Sponsorship
ChipSoft, Castor EDC, Nutricia Nederland BV, Mathys Orthopaedics BV, ABN AMRO, Stichting Anna Fonds|NOREF, Haaglanden Medisch Centrum, Traumacentrum West, the department of Public Health and Primary Care of the LUMC, the Leiden University Libraries.