Leiden University Scholarly Publications

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Abels, E.R.; Broekman, M.L.D.; Breakefield, X.O.; Maas, S.L.N. (2019)

Glioma EVs Contribute to Immune Privilege in the Brain

Article / Letter to editor
Glioblastoma cells release extracellular vesicles (EVs), sometimes referred to as microvesicles and exosomes, to transfer immune modulating molecules to immune cells, resulting in an immune privileged microenvironment. Here we discuss the potential EV-mediated mechanisms underlying glioma immune modulation, as well as the technical difficulties in studying these interactions.
All authors
Abels, E.R.; Broekman, M.L.D.; Breakefield, X.O.; Maas, S.L.N.
Date
2019
Journal
TRENDS IN CANCER
DOI
doi:10.1016/j.trecan.2019.05.006