Multi-wavelength fluorescence in image-guided surgery, clinical feasibility and future perspectives

Beurden, F. van; Willigen, D.M. van; Vojnovic, B.; Oosterom, M.N. van; Brouwer, O.R.; Poel, H.G. van der; ... ; Buckle, T. (2020)

Article / Letter to editor

With the rise of fluorescence-guided surgery, it has become evident that different types of fluorescence signals can provide value in the surgical setting. Hereby a different range of targets have been pursued in a great variety of surgical indications. One of the future challenges lies in combining complementary fluorescent readouts during one and the same surgical procedure, so-called multi-wavelength fluorescence guidance. In this review we summarize the current clinical state-of-the-art in multi-wavelength fluorescence guidance, basic technical concepts, possible future extensions of existing clinical indications and impact that the technology can bring to clinical care.

• image-guided surgery
• fluorescence-guided surgery
• multicolor fluorescence imaging
• multiplexing

• All authors: Beurden, F. van; Willigen, D.M. van; Vojnovic, B.; Oosterom, M.N. van; Brouwer, O.R.; Poel, H.G. van der; Kobayashi, H.; Leeuwen, F.W.B. van; Buckle, T.
• Date: 2020-10-30
• Journal: Molecular Imaging
• Volume: 19
• Pages: 1 - 18
• DOI: doi:10.1177/1536012120962333
• Link: https://journals.sagepub.com/doi/10.1177/1536012120962333