Models with interactions overestimated heterogeneity of treatment effects and were prone to treatment mistargeting

Klaveren, D. van; Balan, T.A.; Steyerberg, E.W.; Kent, D.M. (2019)

Article / Letter to editor

• Personalized medicine
• Heterogeneity of treatment effect
• Treatment benefit
• Prediction models
• Regression analysis
• Penalized regression analysis

• All authors: Klaveren, D. van; Balan, T.A.; Steyerberg, E.W.; Kent, D.M.
• Date: 2019-10-31
• Journal: Journal of Clinical Epidemiology
• Volume: 114
• Pages: 72 - 83
• DOI: doi:10.1016/j.jclinepi.2019.05.029