Comprehensive structure-activity-relationship of azaindoles as highly potent FLT3 inhibitors

Grimm, S.H.; Gagestein, B.; Keijzer, J.F.; Liu, N.; Wijdeven, R.H.; Lenselink, E.B.; ... ; Stelt, M. van der (2019)

Article / Letter to editor

• H-89 analogs
• Fms-like tyrosine kinase 3 (FLT3)
• Acute myeloid leukemia (AML)
• Inhibitors

• All authors: Grimm, S.H.; Gagestein, B.; Keijzer, J.F.; Liu, N.; Wijdeven, R.H.; Lenselink, E.B.; Tuin, A.W.; Nieuwendijk, A.M.C.H. van den; Westen, G.J.P. van; Boeckel, C.A.A. van; Overkleeft, H.S.; Neefjes, J.; Stelt, M. van der
• Date: 2019-03-01
• Journal: Bioorganic and Medicinal Chemistry
• Volume: 27
• Issue: 5
• Pages: 692 - 699
• DOI: doi:10.1016/j.bmc.2019.01.006