New chemotype of selective and potent inhibitors of human delta 24-dehydrocholesterol reductase

Muller, C.; Hemmers, S.; Bartl, N.; Plodek, A.; Korner, A.; Mirakaj, V.; ... ; Bracher, F. (2017)

Article / Letter to editor

• Cholesterol
• Desmosterol
• Steroidal enzyme inhibitors
• 24-Dehydrocholesterol reductase (DHCR24)
• N,N-dimethy1-36-hydroxycholenamide (DMHCA)
• Triparanol

• All authors: Muller, C.; Hemmers, S.; Bartl, N.; Plodek, A.; Korner, A.; Mirakaj, V.; Giera, M.; Bracher, F.
• Date: 2017-11-10
• Journal: European Journal of Medicinal Chemistry
• Volume: 140
• Pages: 305 - 320
• DOI: doi:10.1016/j.ejmech.2017.08.011