Traditional and new composite endpoints in heart failure clinical trials: facilitating comprehensive efficacy assessments and improving trial efficiency

Anker, S.D.; Schroeder, S.; Atar, D.; Bax, J.J.; Ceconi, C.; Cowie, M.R.; ... ; Ruschitzka, F. (2016)

Article / Letter to editor

• Heart failure
• Clinical trial
• Endpoint determination
• Surrogate endpoints

• All authors: Anker, S.D.; Schroeder, S.; Atar, D.; Bax, J.J.; Ceconi, C.; Cowie, M.R.; AdamCrisp; Dominjon, F.; Ford, I.; Ghofrani, H.A.; Gropper, S.; Hindricks, G.; Hlatky, M.A.; Holcomb, R.; Honarpour, N.; Jukema, J.W.; Kim, A.M.; Kunz, M.; Lefkowitz, M.; Floch, C. le; Landmesser, U.; McDonagh, T.A.; McMurray, J.J.; Merkely, B.; Packer, M.; Prasad, K.; Revkin, J.; Rosano, G.M.C.; Somaratne, R.; Stough, W.G.; Voors, A.A.; Ruschitzka, F.
• Date: 2016-05-31
• Journal: European Journal of Heart Failure
• Volume: 18
• Issue: 5
• Pages: 482 - 489
• DOI: doi:10.1002/ejhf.516