Transient complexes of haem proteins

Volkov, O.M. (2007)

Doctoral Thesis

For all organisms populating the Earth, motion is synonymous with life. In the living cell, protein molecules - its most important building blocks and work horses - are constantly on the move. Traditional static models are no longer sufficient for a thorough description of interactions among these biomolecules. Here we present a direct, experimental approach for assessing the dynamics of interactions between proteins, which for a long time has been an exclusive realm of theoretical studies.

• Biomolecular NMR
• Cytochrome
• Encounter state
• Haem
• ITC
• Paramagnetic relaxation enhancement
• Peroxidase
• Protein dynamics
• Spin label
• Transient complex

• All authors: Volkov, O.M.
• Supervisor: Canters, G.W.
• Co-supervisor: Ubbink, M.
• Qualification: Doctor (dr.)
• Awarding Institution: Faculty of Science, Leiden University
• Date: 2007-02-28
• Publisher: Leiden Institute of Chemistry/MetProt Group, Faculty of Mathematics and Natural Sciences, Leiden University
• ISBN (print): 9789090215587