Influence of pharmacogenetic variability on the pharmacokinetics and toxicity of the aurora kinase inhibitor danusertib

Steeghs, N.; Mathijssen, R.H.J.; Wessels, J.A.M.; Graan, A.J. de; Straaten, T. van der; Mariani, M.; ... ; Guchelaar, H.J. (2011)

Article / Letter to editor

• Pharmacogenetics
• Pharmacogenomics
• PHA-739358
• Danusertib
• Cancer: aurora kinase inhibitor

• All authors: Steeghs, N.; Mathijssen, R.H.J.; Wessels, J.A.M.; Graan, A.J. de; Straaten, T. van der; Mariani, M.; Laffranchi, B.; Comis, S.; Jonge, M.J.A. de; Gelderblom, H.; Guchelaar, H.J.
• Date: 2011-10-31
• Journal: Investigational New Drugs
• Volume: 29
• Issue: 5
• Pages: 953 - 962
• DOI: doi:10.1007/s10637-010-9405-7