Determining the genome-wide kinship coefficient seems unhelpful in distinguishing consanguineous couples with a high versus low risk for adverse reproductive outcome

Kelmemi, W.; Teeuw, M.E.; Bochdanovits, Z.; Ouburg, S.; Jonker, M.A.; Alkuraya, F.; ... ; Cornel, M.C. (2015)

Article / Letter to editor

• Inbreeding coefficient
• Relatedness
• Consanguinity
• Autosomal recessive disorder

• All authors: Kelmemi, W.; Teeuw, M.E.; Bochdanovits, Z.; Ouburg, S.; Jonker, M.A.; Alkuraya, F.; Hashem, M.; Kayserili, H.; Haeringen, A. van; Sheridan, E.; Masri, A.; Cobben, J.M.; Rizzu, P.; Kostense, P.J.; Dommering, C.J.; Henneman, L.; Bouhamed-Chaabouni, H.; Heutink, P.; Kate, L.P. ten; Cornel, M.C.
• Date: 2015-07-20
• Journal: BMC Medical Genetics
• Volume: 16
• DOI: doi:10.1186/s12881-015-0191-0