Fusion of hIgG1-Fc to In-111-anti-amyloid single domain antibody fragment VHH-pa2H prolongs blood residential time in APP/PS1 mice but does not increase brain uptake

Rotman, M.; Welling, M.M.; Boogaard, M.L. van den; Moursel, L.G.; Graaf, L.M. van der; Buchem, M.A. van; ... ; Weerd, L. van der (2015)

Article / Letter to editor

• VHH
• Fc fusion
• In-111 labeling
• APPswe/PS1dE9 mice
• Biodistribution
• SPECT

• All authors: Rotman, M.; Welling, M.M.; Boogaard, M.L. van den; Moursel, L.G.; Graaf, L.M. van der; Buchem, M.A. van; Maarel, S.M. van der; Weerd, L. van der
• Date: 2015-08-31
• Journal: Nuclear Medicine and Biology
• Volume: 42
• Issue: 8
• Pages: 695 - 702
• DOI: doi:10.1016/j.nucmedbio.2015.03.003