Combining the pan-aurora kinase inhibitor AMG 900 with histone deacetylase inhibitors enhances antitumor activity in prostate cancer

Paller, C.J.; Wissing, M.D.; Mendonca, J.; Sharma, A.; Kim, E.; Kim, H.S.; ... ; Kachhap, S.K. (2014)

Article / Letter to editor

• AMG 900
• aurora kinase inhibitor
• histone deacetylase inhibitors
• prostate cancer
• synergy
• valproic acid
• vorinostat

• All authors: Paller, C.J.; Wissing, M.D.; Mendonca, J.; Sharma, A.; Kim, E.; Kim, H.S.; Kortenhorst, M.S.Q.; Gerber, S.; Rosen, M.; Shaikh, F.; Zahurak, M.L.; Rudek, M.A.; Hammers, H.; Rudin, C.M.; Carducci, M.A.; Kachhap, S.K.
• Date: 2014-10-31
• Journal: Cancer Medicine
• Volume: 3
• Issue: 5
• Pages: 1322 - 1335
• DOI: doi:10.1002/cam4.289