Persistent Lyme Empiric Antibiotic Study Europe (PLEASE) - design of a randomized controlled trial of prolonged antibiotic treatment in patients with persistent symptoms attributed to Lyme borreliosis

Berende, A.; Hofstede, H.J.M. ter; Donders, A.R.T.; Middendorp, H. van; Kessels, R.P.C.; Adang, E.M.M.; ... ; Kullberg, B.J. (2014)

Article / Letter to editor

• Lyme disease
• Borreliosis
• Persistent symptoms
• Study protocol
• Treatment
• Doxycycline
• Clarithromycin
• Hydroxychloroquine
• Placebo
• Guidelines

• All authors: Berende, A.; Hofstede, H.J.M. ter; Donders, A.R.T.; Middendorp, H. van; Kessels, R.P.C.; Adang, E.M.M.; Vos, F.J.; Evers, A.W.M.; Kullberg, B.J.
• Date: 2014-10-16
• Journal: BMC Infectious Diseases
• Volume: 14
• DOI: doi:10.1186/s12879-014-0543-y