Benzo[a]pyrene-induced transcriptomic responses in primary hepatocytes and in vivo liver: Toxicokinetics is essential for in vivo-in vitro comparisons

Kesteren, P.C.E. van; Zwart, P.E.; Schaap, M.M.; Pronk, T.E.; Herwijnen, M.H.M. van; Kleinjans, J.C.S.; ... ; Luijten, M. (2013)

Article / Letter to editor

• Toxicogenomics
• Carcinogenesis
• Benzo[a]pyrene
• Xpa(-/-)p53(+/-)
• Physiologically based kinetic modeling

• All authors: Kesteren, P.C.E. van; Zwart, P.E.; Schaap, M.M.; Pronk, T.E.; Herwijnen, M.H.M. van; Kleinjans, J.C.S.; Bokkers, B.G.H.; Godschalk, R.W.L.; Zeilmaker, M.J.; Steeg, H. van; Luijten, M.
• Date: 2013-03-31
• Journal: Archives of Toxicology
• Volume: 87
• Issue: 3
• Pages: 505 - 515
• DOI: doi:10.1007/s00204-012-0949-5