Aging as Accelerated Accumulation of Somatic Variants: Whole-Genome Sequencing of Centenarian and Middle-Aged Monozygotic Twin Pairs

Ye, K.; Beekman, M.; Lameijer, E.W.; Zhang, Y.J.; Moed, M.H.; Akker, E.B. van den; ... ; Slagboom, P.E. (2013)

Article / Letter to editor

• aging
• next gen sequencing
• somatic mutations
• twin discordances
• human genome

• All authors: Ye, K.; Beekman, M.; Lameijer, E.W.; Zhang, Y.J.; Moed, M.H.; Akker, E.B. van den; Deelen, J.; Houwing-Duistermaat, J.J.; Kremer, D.; Anvar, S.Y.; Laros, J.F.J.; Jones, D.; Raine, K.; Blackburne, B.; Potluri, S.; Long, Q.; Guryev, V.; Breggen, R. van der; Westendorp, R.G.J.; Hoen, P.A.C. 't; Dunnen, J. den; Ommen, G.J.B. van; Willemsen, G.; Pitts, S.J.; Cox, D.R.; Ning, Z.M.; Boomsma, D.I.; Slagboom, P.E.
• Date: 2013-12-31
• Journal: Twin Research and Human Genetics
• Volume: 16
• Issue: 6
• Pages: 1026 - 1032
• DOI: doi:10.1017/thg.2013.73