Inflammatory Cells in Patients with Endstage Knee Osteoarthritis: A Comparison between the Synovium and the Infrapatellar Fat Pad

Author(s):
Klein-Wieringa, I.R.; Lange-Brokaar, B.J.E. de; Yusuf, E.; Andersen, S.N.; Kwekkeboom, J.C.; Kroon, H.M.; Osch, G.J.V.M. van; Zuurmond, A.M.; Stojanovic-Susulic, V.; Nelissen, R.G.H.H. (0000-0003-1228-4162); Toes, R.E.M. (0000-0002-9618-6414); Kloppenburg, M.; Ioan-Facsinay, A.
Published
2016
Publication type
Article / Letter to editor

Abstract

Conclusion. Our data suggest that the immune cell composition of the synovium and the IFP is similar, and includes activated cells that could contribute to inflammation through secretion of proinflammatory cytokines. Moreover, preliminary analyses indicate that synovial CD4+ T cells might associate with pain in patients with endstage OA of the knee.

OSTEOARTHRITISSYNOVITISIMMUNE SYSTEMPAININFRAPATELLAR FAT PADKNEE
Date issued
2016-04-01
Language
English
Publisher
J RHEUMATOL PUBL CO
Is part of
Journal of Rheumatology (2016), Vol. 43, no. 4, p. 771-778
hdl
1887/99455
doi
10.3899/jrheum.151068